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E SCO4542 family, but is an `orphan' lacking neighbouring whiJ- or SCO4544-like genes. It is curious that bldB is the only classical bld gene to be confined to, yet universal among, streptomycetes (Fig. 3). We speculate that the bald phenotype of bldB mutants could imply a promiscuous interaction of BldB with WhiJ-like proteins encoded elsewhere in the genome and that this may be connected with th
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